李宗儒 (Tsung-Lu Michael Lee)

Title:
Assistant Professor 助理教授 
Office:
C204-3
Phone:
+886-6-253-3131 ext. 3225
e-mail:
michaelee@stust.edu.tw
Lab:
Generative AI Lab - 生成式AI實驗室
Research Interest
Generative AI, Large Language Models, Artificial intelligence、Deep learning、Medical image recognition、Bioinformatics、Biomedical literature mining、MR(AR/VR) 
  Google ScholarTsung-Lu Michael Lee's Google Scholar
 ResearchGateTsung-Lu-Lee's ResearchGate
  ORCID
Tsung-Lu Michael Lee's ORCID

 Education

National Cheng Kung University, Tainan, Taiwan
Ph.D.
Computer Science and Information Engineering
University of Florida, FL, USA
Master
Computer and Information Science and Engineering
University of Iowa, IA, USABachelor
 Computer Science, Biochemistry



[*生成式AI實驗室*]

 歡迎對以下主題有興趣,且對程式開發與創新應用,有興趣的同學加入我們。
 專題和研究主
  1. 生成式AI - ChatGPT應用、聊天機器人開發 [延伸閱讀]
  2. 大型語言模型(LLMs) - LLMs開發與訓練 [延伸閱讀]
  3. 人工智慧與應用 - 各類型AI之框架(如tensorflowPyTorch)開發與應用。
  4. 深度學習 - 模型訓練、transfer learning。
  5. MR 混合實境 - MR Unity程式開發(佐臻AR[官網]、微軟HoloLens [微軟HoloLens 2教學])
  6. 物聯網 - 數莓派影像辨識與應用
  7. 運動科技與人工智慧應用 (運動科技是下一個兆元產業 [全文])
Welcome to join Generative AI Lab
If you are interested in one of the topics below, you are more than welcome to visit and join our lab.

(*Undergraduate/Graduate students are both welcome)

 Undergraduate
and
Graduate
Topics
  1. Generative AI - Applications using ChatGPT、AI Chat Bots
  2. Large Language Models(LLMs) - LLMs development
  3. Artificial Intelligence and Applications - AI frameworks(ex. tensorflow, PyTorch)development and applications.
  4. Deep Learning - model training with transfer learning
  5. MR (Mixed Reality) - MR Unity Programming (Jorjin AR devices、Microsoft HoloLens)
  6. IoT - Raspberry pi image recognition and its applications
  7. Sports Science and Technology and AI Applications






Reviewer / Committee

 AMIA 2024 Informatics Summit Scientific Program Committee Award [Reviewer] – Tsung-Lu Michael Lee   [Awarded: Mar. 21, 2024]
2024 Symposium on Digital Life Technologies (2024/5/17-18) - [Conference Special Session Committee]
18th International Conference on Immovaiton, Management, and Knowledge Community (iCIMKC) 2024 (2024/5/24) 
- [Reviewer] 
2023 International Symposium on Novel and Sustainable Technology (2023 ISNST) (2023/10/19-20)- [Technical Committee]
AMIA 2023 Informatics Summit - [Reviewer] 
AMIA 2021 Informatics Summit - [Reviewer] 

Publications (Journal Papers) 

Year
Publications (Journal papers)
2023 Histopathology Images Predicted Multi-Omics Aberrations and Prognoses in Colorectal Cancer Patients.
Authors:  Pei-Chen Tsai, Tsung-Hua Lee, Kun-Chi Kuo, Fang-Yi Su, Tsung-Lu Michael Lee, Eliana Marostica, Tomotaka Ugai, Melissa Zhao, Mai Chan Lau, Juha P. Väyrynen, Marios Giannakis, Yasutoshi Takashima, Seyed Mousavi Kahaki, Kana Wu, Mingyang Song, Jeffrey A. Meyerhardt, Andrew T. Chan, Jung-Hsien Chiang, Jonathan Nowak, Shuji Ogino, Kun-Hsing Yu.
Nature Communications. 2023 Apr 13;14(1):2102. [Pubmed] [Codes] 
 (IF: 17.694)

Fig. 1: An overview of the Multi-omics Multi-cohort Assessment (MOMA) machine learning framework.Fig. 1: An overview of the Multi-omics Multi-cohort Assessment (MOMA) machine learning framework.
2020
Reproducible Machine Learning Methods for Lung Cancer Detection Using Computed Tomography Images: Algorithm Development and Validation. 
Authors:  Kun-Hsing Yu, Tsung-Lu Michael Lee, Ming-Hsuan Yen, S C Kou, Bruce Rosen, Jung-Hsien Chiang, Isaac S Kohane. 
Journal of Medical Internet Research. 2020 Aug 5;22(8):e16709.  
 (IF: 7.4)

  • PMID: 32755895
  •  
  • PMCID: PMC7439139
  • DOI: 10.2196/16709 
  • [Pubmed]

    A model of the informatics workflow used by most teams. In addition to the Kaggle training set, most teams obtained additional publicly available datasets with annotations. Lung segmentation, image rescaling, and nodule segmentation modules were commonly used before classification.A model of the informatics workflow used by most teams. In addition to the Kaggle training set, most teams obtained additional publicly available datasets with annotations. Lung segmentation, image rescaling, and nodule segmentation modules were commonly used before classification.
    2018
    A Cloud-Based Metabolite and Chemical Prioritization System for the Biology/Disease-Driven Human Proteome Project. 
    Authors:  Kun-Hsing Yu, Tsung-Lu Michael Lee, Yu-Ju Chen, Christopher Ré, Samuel C Kou, Jung-Hsien Chiang, Michael Snyder, Isaac S Kohane. 
    Journal of Proteome Research. 2018 Dec 7;17(12):4345-4357. (IF: 5.37)

  • PMID: 
    30094994
  •  
  • PMCID: PMC6599684
  •  
  • DOI: 10.1021/acs.jproteome.8b00378
  • [Pubmed] 
    2018
    Systematic Protein Prioritization for Targeted Proteomics Studies through Literature Mining.
    Authors:  Kun-Hsing Yu, Tsung-Lu Michael Lee, Chi-Shiang Wang, Yu-Ju Chen, Christopher Ré, Samuel C Kou, Jung-Hsien Chiang, Isaac S Kohane, and Michael Snyder.
    Journal of Proteome Research. 2018 Apr 6;17(4):1383-1396. (IF: 5.37)
    2016Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
    Authors:  Tze-Sian Chan, Chung chi Hsu, Vincent C. Pai, Wen-Ying Liao, Shenq-Shyang Huang, Kok-Tong Tan, Chia-Jui Yen, Shu-Ching Hsu, Wei-Yu Chen, Yan-Shen Shan, Chi-Rong Li, Michael T. Lee, Kuan-Ying Jiang, Jui-Mei Chu, Gi-Shih Lien, Valerie M. Weaver, Kelvin K. Tsai.
    Journal of Experimental Medicine (JEM) 2016 Dec 12;213(13):2967-2988.  
    (IF: 17.579)

    2013
    A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression.
    Authors: Wei-Yu Wang, Chung-Chi Hsu, Ting-Yun Wang, Chi-Rong Li, Ya-Chin Hou, Jui-Mei Chu, Chung-Ta Lee, Ming-Sheng Liu, Jimmy J-M Su, Kuan-Ying Jian, Shenq-Shyang Huang, Shih-Sheng Jiang, Yan-Shen Shan, Pin-Wen Lin, Yin-Ying Shen, Michael T-L Lee, Tze-Sian Chan, Chun-Chao Chang, Chung-Hsing Chen, I-Shou Chang, Yen-Ling Lee, Li-Tzong Chen, Kelvin K Tsai.  
    Gastroenterology. 2013 Nov;145(5):1110-20. 
    (IF: 33.883)

    2013
    Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer. 
    Authors: Chi-Rong Li, Jimmy J-M Su, Wei-Yu Wang, Michael T-L Lee, Ting-Yun Wang, Kuan-Ying Jiang, Chein-Feng Li, Jong-Ming Hsu, Chi-Kuan Chen, Marcelo Chen, Shih-Sheng Jiang, Valerie M Weaver, Kelvin K-C Tsai.
    American Journal of Pathology. 2013 Feb;182(2):363-74. 
    (IF: 5.77)

  • PMID: 23219426
  •  
  • PMCID: PMC3562735
  •  
  • DOI: 10.1016/j.ajpath.2012.10.024

  • 2012
    A Systems Biology Approach to Solving the Puzzle of Unknown Genomic Gene-Function Association Using Grid-Ready SVM Committee Machines
    Authors: Tsung-Lu Michael Lee and Jung-Hsien Chiang. 
    IEEE Computational Intelligence Magazine. 2012 Nov;vol. 7, no. 4, pp. 46-54. (IF: 9.809)

    DOI: 10.1109/MCI.2012.2215126
    2009
    Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. 
    Authors: Ravindra Majeti, Michael W Becker, Qiang Tian, Tsung-Lu Michael Lee, Xiaowei Yan, Rui Liu, Jung-Hsien Chiang, Leroy Hood, Michael F Clarke, Irving L Weissman. 
    Proc Natl Acad Sci U S A. 2009 Mar;3;106(9):3396-401. 
    (IF: 12.779)

    2008
    In Silico Prediction of Human Protein Interactions Using Fuzzy–SVM Mixture Models and Its Application to Cancer Research
    Authors: Jung-Hsien Chiang and Tsung-Lu Michael Lee.
    IEEE Transactions on Fuzzy Systems. 2008 Aug;vol. 16, no. 4, pp. 1087-1095. (IF: 12.253)

    Publications (Conference Papers/ arXiv Preprints)

    Year
    Publications (Conference papers)
    2021 CUAB: convolutional uncertainty attention block enhanced the chest x-ray image analysis.
    Authors: Chi-Shiang Wang; Fang-Yi Su; Tsung-Lu Michael Lee; Yi-Shan Tsai; Jung-Hsien Chiang
    2021 | Preprint
    DOI:  10.48550/ARXIV.2105.01840
    2016Condensedly: comprehending article contents through condensed texts.
    Authors: Chao-Hsuan Ke; Tsung-Lu Michael LeeJung-Hsien Chiang
    2016 | Preprint
    DOI: 10.48550/ARXIV.1612.09062
    2015An Integrated Cloud-based Next-Generation Sequencing Analysis Recommender and Its Application to Bioinformatics Teaching. 
    Authors: Tsung-Lu Michael Lee
    5th Annual Next Generation Sequencing Asia Congress & 3rd Annual Single Cell Analysis Asia Congress Biopolis, Singapore, October 13-14, 2015.
    2015 CoTri: extracting chemical–disease relations with co-reference resolution and common trigger words. 
    Authors: Yu-De Chen, Juin-Huang Ju, Ming-Yu Chien, Yu-Cheng Sheng, Tsung-Lu Lee, Jung-Hsien Chiang
    Proceedings of the Fifth BioCreative Challenge Evaluation Workshop. Sevilla, Spain., 2015. p. 286-291.
    [Research NCKU]
    2013Gene signature and systems biology approaches in the understanding of drug-to-disease mechanisms.
    Authors: Tsung-Lu Michael Lee
    3rd Next Generation Sequencing Asia Congress, Singapore, Oct. 8-9, 2013.
    2012C2HI: A Complete CHemical Information decision system.
    Authors: Chao-Hsuan KeTsung-Lu Michael Lee Jung-Hsien Chiang
    BioCreative 2012 Workshop, Washington DC USA, April 4-5, 2012.
    2010Gene expression signatures associated with protracted stromal responses to therapeutically relevant cytotoxic stimuli predict breast cancer chemoresponsiveness
    Authors: Michael T.-L. Lee; Jimmy J.-M. Su; Chi-Rong Li; Patrick Y.-W. Chu; Ming-Sheng Liu; Jung-Hsien Chiang; Kelvin K.-C. Tsai; Kok-Tong Tan
    Clinical Cancer Research (2010) 16 (19_Supplement): B22.
    https://doi.org/10.1158/DIAG-10-B22
    2010 A gene expression signature associated with structural differentiation of prostate acini predicts postoperative recurrence of prostate cancer.
    Authors: Jimmy J.-M. Su; Chi-Rong Li; Michael T.-L. Lee; Patrick Y. W. Chu; Valerie M. Weaver; Kelvin K.-C. Tsai
    Clinical Cancer Research (2010) 16(19 Supplement): A22.
    https://doi.org/10.1158/DIAG-10-A22

     證照/證書 Certification

    編號
    名稱
     1大學雙語教師專業發展課程結業證書 *Certificate of Completion of EMI PD courses  [Awarded: Aug. 11, 2023] 
     2IPAS經濟部產業人才能力鑑定物聯網應用工程師[初級]
     3IPAS經濟部產業人才能力鑑定行動裝置程式設計師[初級]

     教育部數位學習課程認證 Ministry of Education E-Learning Course Certification

    編號
    名稱
    1108年度第2梯次教育部數位學習課程認證-通過課程: 機器學習
    2108年度第2梯次教育部數位學習課程認證-通過課程: 手機UI設計
    3108年度第1梯次教育部數位學習課程認證-通過課程: 行動APP程式開發
    4108年度第1梯次教育部數位學習課程認證-通過課程: 計算機網路 

      指導學生參與競賽 Students to participate in contests/competitions

    編號
    名稱
          1【2024電通永續之森 新世代數位公民計畫-複賽(前10名)【2024/3/22(五)複賽-永續創意工作坊 Sustainable Creativity Workshop-Taiwan Secom Co., Ltd. (中興保全科技)
    22023 TCN創客松 - 生活改善設計競賽,晉級決賽 (2023/9/24)  佳作獎金: 1萬元
    參賽隊伍: AI生成進行式
    主辦單位: 勞動部勞動力發展署中彰投分署、TCN創客基地
    32023 X-Run! 創新競賽 南臺科技大學團隊 晉級第二階段 實證訪視(2023/10/2)
    視障保齡球【殘瓶報讀/姿勢校正輔助應用】
    南臺電子-楊峻泓老師,南臺資工-李宗儒老師團隊
    42020經濟部工業局 AI智慧應用新世代人才培育計畫解題競賽(第三階段實證成果) 組別:數據分析類   名次:優等獎 (獎金30萬元)

      全英文課程(EMI Courses)

    Semester
    Courses
     112.2 人工智慧醫療應用  (Artificial Intelligence in Healthcare) [EMI] [全英語] (*本學期開課中 This Semester)
     112.2 深度學習與電腦視覺  (Deep learning for Computer Vision) (*本學期開課中 This Semester)
     112.1 人工智慧與應用  (Artificial Intelligence and Applications) [EMI] [全英語]
     111.2 專題研究(大學部) (Undergraduate Research) [EMI] [全英語]
     111.1 人工智慧 (Artificial Intelligence) [EMI] [全英語]
     111.1 深度學習 (Deep Learning) [EMI] [全英語]
     110.2 機器學習 (Machine Learning) [EMI] [全英語]
     110.2 影像處理 (Image Processing) [EMI] [全英語
     110.1 雲端運算概論 (Intro. to Cloud Computing) [EMI] [全英語]
     109.2 伺服網頁程式設計 (Web Server Programming using Python Flask) [EMI] [全英語]
     109.1 APP程式設計(APP Programming) [EMI] [全英語]
     TOP